Sash1 protein
Webb31 okt. 2006 · SASH1 is a member of the SH3-domain containing expressed in lymphocytes ( SLY1) gene family that encodes signal adapter proteins composed of several protein–protein interaction domains. The... WebbAll members of the SLy/SASH1-protein family contain a bipartite nuclear localization signal (NLS), a central Src homology 3 (SH3) domain and a sterile α motif (SAM) in their C …
Sash1 protein
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Webb10 nov. 2016 · Many proteins have been shown to be cleaved by caspases during apoptosis including the multifunctional protein PARP1 and the human DNA repair nuclease Exo1. 32 The cleavage of SASH1 was shown to ... Webb24 feb. 2024 · In the last decade, numerous circRNAs were discovered by virtue of the RNA-Seq technique. With the deepening of experimental research, circRNAs have brought to light the key biological functions and progression of human diseases. CircRNA ITCH has been demonstrated to be a tumor suppressor in numerous cancers, and recently it was …
Webb25 okt. 2024 · SASH1 is a scaffold protein belonging to the same family as SASH3. Unlike the dimerization seen in SASH3's SAM domain, our SEC-MALS and SE-HPLC showed that SAM1 exists primarily as a less compact ... Webb8 nov. 2016 · Expression of the SASH1 protein is reduced in a range of human cancers and has been implicated in apoptotic cancer cell death. This study investigated whether …
WebbSASH1 mediates sensitivity of breast cancer cells to chloropyramine and is associated with prognosis in breast cancer Burgess JT et al Oncotarget 2016;7(45):72807-72818 … Webb21 mars 2024 · SASH1 (SAM And SH3 Domain Containing 1) is a Protein Coding gene. Diseases associated with SASH1 include Cancer, Alopecia, Pigment Dyscrasia, Onychodystrophy, And Keratoderma and Dyschromatosis Universalis Hereditaria 1 .
Webb15 juli 2013 · SASH1 is a scaffold molecule in endothelial TLR4 signaling. Recognition of microbial products by TLRs is critical for mediating innate immune responses to …
Webb15 okt. 2024 · 2.6. HMGB1 siRNA treatment. We investigated the effects of extracellular HMGB1 on SASH1 gene expression by applying 100 ng/mL of HMGB1 recombinant protein (rHMGB1, 1690-HMB, R&D Systems Co.) to the astrocyte cultures for 60 h and subsequently detecting SASH1 expression through qRT-PCR and WB analysis. The … preparation for booster covid shotWebbOpen Access Depletion of SASH1, an astrocyte differentiation-related gene, contributes to functional recovery in spinal cord injury Siyi Liu, Siyi Liu Department of Neurosurgery, Affiliated Hospital of Nantong University, Nantong, China Search for more papers by this author Ge Lin, Ge Lin preparation for a stress testWebb17 mars 2016 · SAM- and SH3-domain containing 1 (SASH1) is a recently identified tumor suppressor gene that is required in the tumorigenesis of breast and other solid carcinomas. The SASH1 protein contains SH3 and SAM domains, indicating that it may serve an important role in intracellular signal transduction. The purpose of the present study was … scott douthettWebb1 aug. 2013 · SASH1 is the largest member of the protein family, it is encoded by 20 exons. All SLY-family proteins share a central conserved NLS (nuclear localisation signal) sequence, a SH3 and a SAM domain (dotted line). scott douton norwich ctWebb26 sep. 2012 · SASH1 antibody was purchased from Bethyl laboratories Inc. (Montgomery, MA, USA) and the primary GAPDH antibody was purchased from Proteintech Group (Chicago, IL, USA). Cell proliferation assay Proliferation assay was carried out to assess cell viability in the A-375 (SASH1), A-375 (EGFP) and A-375 cell lines. preparation for basic training in the armyWebbImmune cell - SASH1 - The Human Protein Atlas SASH1 IMMUNE CELL CELL LINEAGES Immune cell proteome IMMUNE CELL TYPE EXPRESSION (RNA)i HPA dataseti Lineage … scott dougrayWebbMETABOLIC SASH1 SINGLE CELL TYPE TISSUES Cell type proteome SINGLE CELL TYPESi Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Astrocytes, Oligodendrocytes, Adipocytes, Oligodendrocyte precursor cells, Microglial cells) scott douthitt